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Remote Python Jobs in the United States Paying $50K+ (12 open)

There are 12 remote Python Jobs in the United States Paying $50K+ on CafeRemote right now, newest first. These roles were matched to Python by the skills and category each employer listed, not by keyword guessing. Each one is remote but restricted to candidates who can work from the United States — check the listing for timezone requirements. Applications go directly to the employer; CafeRemote never sits between you and the hiring team.

12 roles · newest first

Senior Backend Engineer

Proton.ai · Americas Only

Full-time Senior the United States $50,000 - $74,999 USD 8mos ago

AI Product Engineer

PostHog · USA, United Kingdom of Great Britain, Northern Ireland

Full-time the United States the United Kingdom 100,000 or more USD 11mos ago

Senior Backend Engineer

Proton.ai · Americas Only

Full-time Senior the United States $50,000 - $74,999 USD 11mos ago

Remote Lead DevOps Engineer

Lemon.io · Latin America Only, Europe Only, UK Only, Canada Only, OCEANIA Only

Full-time Lead Europe $ 75,000 - $ 99,999 USD 1yr ago

Senior AI Engineer - (Remote)

Lemon.io · Latin America Only, Europe Only, Canada Only, UK Only

Full-time Senior Europe $ 75,000 - $ 99,999 USD 1yr ago

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