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Mineralys Therapeutics

Sr. Manager, Commercial Strategic Sourcing

Remote United States Full-time Senior $175K – $195K / year Posted 4h ago
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Work from
United States
Contract
Full-time
Experience
Senior
Salary
$175K – $195K / year
Posted
12 November 2026
Apply by
11 January 2027

This role leads competitive sourcing, contracting, supplier relationship management, and continuous improvement initiatives while partnering cross-functionally with Commercial, Finance, Legal, Compliance, and other key stakeholders.

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

The Senior Manager, Commercial Strategic Sourcing is responsible for developing and executing sourcing strategies across commercial categories to support business objectives, optimize total cost, manage third-party risk, and deliver measurable value.

Principal Responsibilities

  • Develop and execute category strategies for commercial services aligned with business priorities and maximizes the return on investment.
  • Lead end-to-end RFI/RFP processes, vendor evaluations, negotiations, and vendor selection across marketing, media, digital, market access, sales operations, patient services, meetings and events, and other commercial services.
  • Analyze spend, markets, suppliers, proposals, pricing models, and total cost to identify opportunities and support fact-based sourcing decisions.
  • Negotiate and manage MSAs, statements of work, work orders, and change orders with Legal and stakeholders, including pricing, deliverables, milestones, payment terms, service levels, and performance measures.
  • Partner with Commercial, Finance, Legal, Compliance, IT, and other stakeholders to define requirements, influence decisions, and deliver sourcing initiatives on schedule.
  • Manage supplier governance through business reviews, scorecards, KPIs, issue resolution, risk mitigation, and continuous improvement plans.
  • Deliver and report cost savings, cost avoidance, demand management, process efficiency, and other measurable value.
  • Ensure sourcing activities follow ethical practices, internal policies, approval requirements, external regulations, and industry standards.
  • Support budgeting, forecasting, and accruals with contract commitments, pricing assumptions, sourcing insights, and supplier financial information.
  • Improve sourcing processes, templates, tools, and training; educate stakeholders on competitive bidding, contracting, and supplier management requirements.

Requirements

  • Bachelor's degree in Business, Supply Chain, Finance, Life Sciences, or a related field; advanced degree or relevant certification preferred.
  • 6+ years of progressive strategic sourcing, procurement, category management, or supplier management experience, preferably in pharmaceuticals, biotechnology, or life sciences.
  • 3+ years commercial sourcing experience in categories such as marketing, media, digital, market access, sales operations, patient services, meetings and events, or professional services.
  • Proven experience leading competitive sourcing, complex negotiations, contract development, spend analysis, and supplier relationship management.
  • Working knowledge of procurement governance, third-party risk, compliance, and financial management in a regulated environment.
  • Excellent analytical, communication, collaboration, influencing, organization, and problem-solving skills.
  • Ability to work in a fast-paced, matrixed environment.

Skills and Attributes

  • Strong written and verbal communication skills, including well-developed presentation, negotiation, and influencing skills
  • Ability to translate business requirements and market intelligence into practical category and sourcing strategies
  • Strong analytical, financial, problem-solving, and decision-support capabilities
  • Strong customer focus with the ability to build trusted cross-functional relationships
  • Strategic thinking with a pragmatic, results-oriented approach to execution
  • Ability to manage multiple priorities, work independently, and collaborate effectively in a fast-paced, matrixed environment

Travel

  • This position requires up to 10% travel, mainly for training, national and regional meetings. Some travel is outside the local area and overnight.

Salary

US Salary Range: $175,000 - $195,000

Discussion

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