L- Work from
- United States
- Contract
- Full-time
- Experience
- Senior
- Salary
- $97K – $193K / year
- Posted
- 12 November 2026
- Apply by
- 11 January 2027
Whether you're building your career or bringing years of experience, you'll have the opportunity to learn, grow, and help shape the future of clinical research.
Job Title: Senior Clinical Research Associate - CNS / Rare Disease (US, Central)
Job Location: Virtual United States Colorado
Job Location Type: Remote
Job Contract Type: Full-time
Job Seniority Level
Join a global Contract Resource Organization (CRO) where innovation meets purpose. At Worldwide Clinical Trials, we're driven by a shared commitment to improving lives through high-quality clinical research. Our teams are empowered to think creatively, take ownership, and deliver meaningful work that helps bring life-changing therapies to patients around the world.
With more than 4,000 professionals across the globe, we foster a collaborative and inclusive environment where diverse perspectives are valued, growth is encouraged, and every contribution makes an impact.
Make an Impact as a Senior CRA at Worldwide
As a Senior CRA, you’ll play a critical role in ensuring clinical studies are conducted with the highest standards of quality, patient safety, and regulatory compliance. Your expertise will help drive the successful execution of studies from site qualification through closeout, supporting the delivery of reliable data that advances clinical research.
In this role, you'll serve as a trusted partner to investigative sites, study teams, and sponsors, building strong relationships while providing leadership, guidance, and oversight across clinical trial activities. You’ll have the opportunity to influence study success through proactive monitoring, site management, and collaboration with global teams.
Your contributions will directly support high-quality study delivery by ensuring protocol adherence, regulatory compliance, timely data collection, and effective site performance throughout the clinical trial lifecycle.
Where You'll Work
This is a home-based Clinical Research Associate role supporting sites across the Midwest of the United States. You will collaborate with sites, sponsors, and global study teams while traveling to investigative sites approximately 8-10 days per month.
To best support our sites, we're seeking candidates who are based in the Midwest of the United States. Travel will primarily be regional, with occasional travel to support sites in other locations as needed.
Responsibilities
- Manage clinical research activities at investigative sites participating in Worldwide clinical studies.
- Identify and assess potential research sites to support successful study execution.
- Coordinate study start-up activities, including collection of regulatory documentation and support of contract and budget processes.
- Conduct all types of monitoring visits: Pre-Site Selection Visits (PSSVs), Study Initiation Visits (SIVs),Interim Monitoring Visits (IMVs) and Closeout Visits (COVs).
- Train site personnel on protocol requirements, data collection processes, and safety reporting expectations.
- Monitor site performance and provide ongoing support throughout study maintenance activities.
- Ensure compliance with informed consent requirements, safety reporting obligations, and applicable regulatory standards.
- Partner with sites and study teams to drive data quality, participant safety, and overall study success.
- Support site closeout activities and ensure study requirements are completed at the conclusion of the trial.
Requirements
- Bachelor's Degree or a Nursing Degree, along with 5+ years as a regional, traveling Clinical Research Associate.
- Required experience monitoring CNS and Rare Disease clinical trials.
- Requires travel within the specified region; 8 – 10 DOS monthly
- Experience in full-service monitoring preferred.
- Strong knowledge of clinical trial processes, site management, and regulatory requirement
Eligibility
- Candidates must reside within the territory to effectively support site visits and study activities.
Discover the Difference
We love knowing that someone is going to have a better life because of the work we do. Discover the Difference at Worldwide Clinical Trials. Explore additional opportunities on our careers page, visit, or connect with us on LinkedIn.
At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.
The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):
United States of America - $97,000.00 - $193,000.00
The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.
Worldwide is an equal opportunity employer that is committed to enabling professionals from all backgrounds and experiences to succeed and, to that end, we prioritize attracting diverse talent and cultivating an inclusive environment that encourages collaboration and creativity. We know that when our employees feel appreciated and included, they can be more creative, innovative, and successful. We’re on a mission to hire the very best and are committed to creating exceptional employee experiences where everyone is respected and has access to equal opportunity. We provide equal employment opportunities to all employees and applicants regardless of race, color, ethnicity, ancestry, religion, national origin, gender, sex, gender identity or expression, sexual orientation, age, citizenship, marital or parental status, disability, military status, or other class protected by applicable law.
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