Senior Clinical Research Associate - CNS/Rare Disease - Midwest

Worldwide Clinical Trials is hiring a Senior Clinical Research Associate for CNS and rare disease studies. The role is remote, but candidates must live in the Midwest and be willing to travel regionally to visit sites. This is a full-time position for someone with at least five years of CRA experience who has worked in rare disease and CNS.

What you will do

You will manage research activities at sites taking part in Worldwide's clinical research projects. The work covers all stages of a study:

• Identify potential sites to participate in the research
• Handle study start-up tasks, including collecting regulatory documents from sites and supporting the negotiation of contracts and budgets
• Train sites to collect data properly and report potential safety-related events
• Manage site activities during study maintenance
• Close down research activities at sites once the study has concluded
• Conduct study initiation visits (SIVs)

Most site management is done remotely. You will still be required to ensure compliance with obtaining informed consent, reporting potential safety-related events, and following all applicable regulatory requirements.

What they are looking for

• 5+ years of experience as a Clinical Research Associate
• Experience in rare disease and CNS, which is required
• A 4-year university degree or a nursing degree
• Excellent interpersonal, oral, and written communication skills in English
• Strong organizational skills with attention to detail
• Ability to work with little or no supervision
• Proficiency in Microsoft Office, CTMS, and EDC systems
• Candidates must reside in the Midwest
• Willingness to travel regionally

Pay and benefits

The salary range for this position is $97,000.00 to $193,000.00 per year. The final salary depends on relevant experience, performance, education, and internal equity. A competitive benefits package is offered depending on location. Salary information will be discussed during the interview process.

About the company

Worldwide Clinical Trials is a global, midsize CRO with more than 3,500 employees. The company describes its teams as clinicians, scientists, and researchers working to make healthcare better, and says it was founded on personalized attention. Clinical Operations staff work across therapeutic areas including cardiovascular, metabolic, neuroscience, oncology, and rare diseases. The company says CRAs receive support through regulatory submissions, TMF management, and in-house CRAs for projects with heavy site management needs, plus regular coaching with a line manager. The career path can lead to Clinical Trial Manager roles.

Role details

• Req ID: JR102486
• Posted: 2026-07-15
• Employment type: Full-time
• Work location: Remote
• Location: Virtual United States, Ohio, United States of America